Systemic cardiovascular inflammation associated with autoimmune disease

Epilepsy associated with systemic autoimmune disorders.

Systemic autoimmune disorders affect multiple organ systems. Brain involvement commonly causes seizures, which may be the presenting symptom. Systemic lupus erythematosus, Sjorgren's syndrome, Wegener's granulomatosis, sarcoidsosis, celiac disease, Crohn's disease, Behcet's, and Hashimoto's encephalopathy are reviewed. Mechanisms underlying CNS pathology in systemic autoimmune disorders-and spe...

Systemic inflammation in cardiovascular and periodontal disease: comparative study.

Epidemiological studies have implicated periodontal disease (PD) as a risk factor for the development of cardiovascular disease (CVD). These studies addressed the premise that local infection may perturb the levels of systemic inflammatory mediators, thereby promoting mechanisms of atherosclerosis. Levels of inflammatory mediators in the sera of subjects with only PD, only CVD, both diseases, o...

Leukocytes Link Local and Systemic Inflammation in Ischemic Cardiovascular Disease

[Systemic autoimmune disease in patients with uveitis].

OBJECTIVE A descriptive study was conducted on patients with uveitis to determine the frequency of associated autoimmune systemic diseases. METHODS 64 patients with uveitis were studied. The patients were not known to have an underlying autoimmune systemic disease prior to the diagnosis of uveitis. All patients had the following immunological tests performed: serum immunoglobulins, complement...

Myocardial disease in systemic vasculitis and autoimmune disease detected by cardiovascular magnetic resonance.

SIR, Cardiovascular disease is a major cause of morbidity and mortality in patients with inflammatory autoimmune and vasculitic diseases such as systemic lupus erythematosus (SLE) and Wegener’s granulomatosis (WG) [1, 2]. An increased prevalence of subclinical atherosclerotic disease on carotid ultrasound [3] and coronary Electron Beam Computed Tomography (EBCT) [4] has led to the suggestion th...